CTRP3 Antilichaam

CTRP3 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It has been suggested that CTRP3 may play a role in skeletal development.

114899

Q9BXJ4

NP_852100

Human, Mouse, Rat

3565

Unconjugated

Primary Antibodies

Recombinant Protein Test (Figure 2) : Anti-CTRP3 antibodies (3565) detected human CTRP3 recombinant protein. Recombinant Protein Test3565

Signal Transduction

CTRP3 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1401 - Mouse Heart Tissue Lysate

1 mg/mL

CTRP3 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

CTRP3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

Multiple isoforms of CTRP3 are known to exist. CTRP3 antibody is predicted to not recognize other members of the CTRP protein family.

Human CTRP3 has 3 isoforms, including isoform 1 (246aa, 27kD), isoform 2 (198aa, 22kD) and isoform 3 (319aa, 35kD) . Mouse CTRP3 has one isoform (246aa, 27kD) and Rat CTRP3 also has one isoform (319aa, 35kD) . 3565 can detect human, mouse and rat.

C1QTNF3

Cat. No. 1203 - A549 Cell Lysate

Cat. No. 1205 - Jurkat Cell Lysate

Cat. No. 1282 - 3T3/NIH Cell Lysate

C1q and tumor necrosis factor related protein 3

Homo sapiens

Fantuzzi. J. Allergy Clin. Immunol. 2005; 115:911-9.

Tsao et al. Euro. J. Pharmacol. 2002; 440:213-21.

Wong et al. Proc. Natl. Acad. Sci. USA 2004; 101:10302-7.

Shapiro and Scherer. Curr. Biol. 1998; 8:335-8.

CTRP3 Antibody: CORS, CORCS, CTRP3, CORS26, C1ATNF3, CORS-26, UNQ753/PRO1484, Complement C1q tumor necrosis factor-related protein 3, Collagenous repeat-containing sequence 26 kDa protein

ELISA, WB, IHC-P, IF

62739183

Liquid