CTSD Antilichaam

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

1509

P07339

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 65-412 of human CTSD (NP_001900.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

Mouse kidney

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 45kDa

IgG

CTSD

Mouse heart

Cathepsin D

Homo sapiens

CTSD, CPSD, CLN10, Lysosomal aspartyl peptidase, Lysosomal aspartyl protease, ProCathepsin D, CatD, Cathepsin D

WB, IHC, IF

Liquid