CTTN Antilichaam

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

2017

Q14247

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CTTN (NP_612632.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction

Affinity purification

Mouse liver

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 61kDa

IgG

CTTN

Rat liver

Rat kidney

Cortactin

Homo sapiens

CTTN, EMS1, FLJ34459

WB, IHC, IF

Liquid