CTX-1211

CTX-1211 is a selective, orally effective melanocortin MC4R agonist (EC50=0.38 nM). CTX-1211 can enhance the feeding suppression and weight loss effects induced by liraglutide , and promote anorexia and weight loss activity. CTX-1211 is mainly used in the study of obesity and other metabolic disorders[1].

12352209

Melanocortin Receptor

GPCR/G Protein; Neuronal Signaling

Metabolic Disease

O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CSSC[C@@H](C(N)=O)NC1=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCNC(N)=N)C(N[C@H]1CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O)=O)=O)C

C57H83N21O15S2

1366.53

[1]Dahir NS, et al. Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents. bioRxiv [Preprint]. 2023 Dec 7:2023.12.05.570114.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10985/

Peptides

No Development Reported

MC4R