CUL3 Antilichaam

This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

8452

Q13618

Human, Mouse, Rat

Recombinant protein of human CUL3

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 82kDa, 84kDa

IgG

CUL3

U-251MG

Jurkat

PC-12

Mouse brain

Mouse spleen

Cullin 3

Homo sapiens

CUL3, cullin 3, KIAA0617

WB, IHC, IF

Liquid