Curcumine

458-37-7

Diferuloylmethane, Natural Yellow 3, Turmeric yellow

C08093-50mg

NF-κB

NF-κB

COC1=C (C=CC (=C1) C=CC (=O) CC (=O) C=CC2=CC (=C (C=C2) O) OC) O

C21H20O6

Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae) . It is an inhibitor of p300 histone acetylatransferase (IC50~25 μM) and Histone deacetylase (HDAC) ; activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle arrest with antitumor activity. Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death. Curcumin exhibits anti-infective properties against various human pathogens like the influenza virus, hepatitis C virus, HIV and so on.

2 years -80 in solvent