CVS-1123
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CVS-1123 is an orally active direct thrombin inhibitor. CVS-1123 inhibits in vitro platelet aggregation of γ-thrombin and prolongs activated partial thromboplastin time. CVS-1123 alters the thrombotic response to deep vessel wall damage in arterial and venous circulation. CVS-1123 can be used in antithrombotic studies[1][2]
151275-19-3
12352005
Thrombin
Metabolic Enzyme/Protease
Cardiovascular Disease
O=C([C@H](CC(OC)=O)NC(C(CCC)CCC)=O)N1[C@H](C(N[C@H](C=O)CCCNC(N)=N)=O)CCC1
C24H42N6O6
510.63
[1]Rebello SS, et al. CVS-1123, a direct thrombin inhibitor, prevents occlusive arterial and venous thrombosis in a canine model of vascular injury. J Cardiovasc Pharmacol. 1997 Feb;29 (2) :240-9.|[2]Cousins GR, et al. Orally effective CVS-1123 prevents coronary artery thrombosis in the conscious dog. Circulation. 1996 Oct 1;94 (7) :1705-12.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19222/
Reference compound1
Phase 1
Beschrijving
CVS-1123 is an orally active direct thrombin inhibitor. CVS-1123 inhibits in vitro platelet aggregation of γ-thrombin and prolongs activated partial thromboplas
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