CX3CR1 Antilichaam

CX3CR1 Antibody: CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was initially identified as the receptor for the transmembrane molecule fractalkine, and renamed CX3CR1. CX3CR1 is known to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.

1524

P49238

NP_001328

Human

Unconjugated

Primary Antibodies

Chemokines & Cytokines, Cancer

CX3CR1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1208 - THP-1 Cell Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Rat: (100%), Rabbit: (93%), Mouse: (93%), Bovine: (86%)

CX3CR1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

CX3CR1 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.

IgG

At least two isoforms of CX3CR1 are known to exist.

CX3CR1

Cat. No. 1212 - 3T3 Cell Lysate

Cat. No. 17-008 - THP-1 Cell Slide

Chemokine (C-X3-C motif) receptor 1

Homo sapiens

Raport CJ, Schweickart VL, Eddy RL JR, et al. The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues. Gene 1995; 163:295-9

Combadiere C, Ahuja SK , and Murphy PM. Cloning, chromosomal localization, and RNA expression of a human β chemokine receptor-like gene. DNA Cell Biol. 1995;14:673-80

Combadiere C, Gao J, Tiffany HL, et al. Gene cloning, RNA distribution, and functional expression of mCX3CR1, a mouse chemotactic receptor for the CX3C chemokine fractalkine. Biochem. Biophys. Res. Commun. 1998; 253:728-32

Harrison JK, Barber CM, and Lynch KR. cDNA cloning of a G-protein-coupled receptor expressed in rat spinal cord and brain related to chemokine receptors. Neurosci. Lett. 1994; 169:85-9

CX3CR1 Antibody: V28, CCRL1, GPR13, CMKDR1, GPRV28, CMKBRL1, CX3C chemokine receptor 1, Beta chemokine receptor-like 1, C-X3-C CKR-1

ELISA, WB, IHC-P, IF

4503171

Liquid