Cx40 Antilichaam / Connexin 40 / GJA5

Connexin 40 protein, also known as Cx40, GJA5 and Gap junction alpha-5 protein, plays a role in cell communication and proper function within the body. In the brain, Connexin 40 helps facilitate communication between neurons, allowing for proper cognitive function and coordination. Research suggests that disruptions in Connexin 40 expression may contribute to neurological disorders such as epilepsy and Alzheimer's disease. In the immune system Gap junctions formed by Connexin 40 facilitate the transfer of signaling molecules between immune cells, enabling a coordinated response to pathogens and foreign invaders.

Western blot: 1:2000-1:4000, Immunohistochemistry (FFPE) : 1:100-1:500

P36382

Human, Mouse

A portion of amino acids 102-134 from the human protein was used as the immunogen for this Cx40 antibody.

WB, IHC-P

Purified

This Cx40 antibody is available for research use only.

Aliquot the Cx40 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

Titration of the Cx40 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Western blot testing of 1) human Jurkat, 2) human HepG2 and 3) mouse brain tissue lysate with Cx40 antibody. Predicted molecular weight ~40 kDa.