CXCR4 Antilichaam - N-terminal regio : HRP (ARP30799_P050-HRP)

Chemokine (C-X-C motif) receptor 4

FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LAP-3, LESTR, NPY3R, NPYRL, WHIMS, HSY3RR, NPYY3R, D2S201E

7852

P61073

NP_003458

Human, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR4

CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UBC; ITCH; nef; P4HB; CD4; env; MYBL2; ST13; ATP13A2; CXCL12; PTPN11; STAM; CAV1; SUMO4; HLA-C; SDC4; HSPA8; GNA13; STAT5B; SOCS3; SOCS1; CCR5; PTK2; STAT2; STAT1; JAK3; DPP4; PTPN6; VAV1; CXCR4; MYH9; PTPRC; JAK2; JAK1; GNAI1; ELANE; CTSG; ADRBK2; ARRB2

HRP: Horseradish Peroxidase

Polyclonal Antibody

FC, IHC, WB

Affinity Purified

0.5 mg/ml

Horse: 89%; Human: 91%; Mouse: 77%; Pig: 91%; Rabbit: 85%; Rat: 77%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

40kDa

Yoshitake, N., (2008) Br. J. Cancer 98 (10), 1682-1689

Wet Ice

352

CXCR4

CXCR4

Rabbit

C-X-C chemokine receptor type 4

NM_003467

MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFL