Cycline C (fosfo Ser275) Antilichaam

The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.

892

P24863

NP_005181.2

Human, Mouse, Rat

Cyclin C (phospho Ser275) antibody was raised against a peptide sequence around phosphorylation site of Serine 275 (N-G-S (p) -A-N) derived from Human Cyclin C.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

37 kDa

IgG

The antibody detects endogenous levels of Cyclin C only when phosphorylated at serine 275.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

CCNC

Cyclin C

Homo sapiens

Lew D.J., Cell 66:1197-1206 (1991) .

Li H., Genomics 32:253-259 (1996) .

Mungall A.J., Nature 425:805-811 (2003) .

CG1C, cyclin C, SRB11

WB, IHC

61676093

Liquid