Cycline F (CCNF) (NM 001761) Humaan Recombinant Proteïne

This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008]

Purified recombinant protein of Human cyclin F (CCNF), Cys496-End, with N-terminal His tag, expressed in E. coli, 50ug

FBX1; FBXO1; FTDALS5

899

P41002, Q59HD0

NM_001761

16p13.3

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0.

Druggable Genome

31.6 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

CCNF

Human

NP_001752

https://www.ncbi.nlm.nih.gov/gene/899

https://www.uniprot.org/uniprot/P41002

https://www.ncbi.nlm.nih.gov/nuccore/NM_001761

https://www.ncbi.nlm.nih.gov/nuccore/NP_001752