Cynomolgus IRAK4 Proteïne, Zijn Tag (active enzym)

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 53.6 kDa. The protein migrates as 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Met 1 - Ser 460

IRAK4

Unconjugated

N-10xHis

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

1.0 EU per μg

90%

Liquid

50 mM HEPES, 300 mM NaCl, pH7.5

53.6 kDa

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Dry ice

-70°C

1mg*1

InsectCells

Cynomolgus

A0A2K5V3Y9

Glycerol