CYP11A1 Antilichaam - middengebied: FITC (ARP51905 P050-FITC)

Cytochrome P450, family 11, subfamily A, polypeptide 1

CYP11A, CYPXIA1, P450SCC

1583

P05108

NP_000772

Human

The immunogen is a synthetic peptide directed towards the middle region of human CYP11A1

CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11A1 localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.

SMAD9; SMAD3; SMAD2; CYP11B2; FDX1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

CYP11A1 is supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

57kDa

Shigematsu, K., (2008) Eur. J. Endocrinol. 158 (6), 867-878

Wet Ice

521

CYP11A1

CYP11A1

Rabbit

Cholesterol side-chain cleavage enzyme, mitochondrial

NM_000781

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