CYP17A1 Antilichaam

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

1586

P05093

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 209-508 of human CYP17A1 (NP_000093.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Growth Factors, Signal Transduction

Affinity purification

Rat testis

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 57kDa

IgG

WB: 1:500 - 1:2000

CYP17A1

Cytochrome P450, family 17, subfamily A, polypeptide 1

Homo sapiens

CYP17A1, cytochrome P450, family 17, subfamily A, polypeptide 1, HGNC:2593, CPT7, CYP17, P450C17, S17AH, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia, cytochrome p450 XVIIA1, steroid 17-alpha-hydroxylase/17, 20 lyase, steroid 17-alpha-monooxygenase

WB

Liquid