CYP27A1 Antilichaam - middengebied: Biotine (ARP51772 P050-Biotine)

Cytochrome P450 family 27 subfamily A member 1

CTX, CP27, CYP27

1593

Q02318

NP_000775

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of Human CP27A

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.

PRDX4

Biotin

Polyclonal Antibody

WB

Affinity purified

0.5 mg/ml

Cow: 77%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

58kDa

Wet Ice

531

CYP27A1

CYP27A1

Rabbit

Sterol 26-hydroxylase, mitochondrial

MTRLDQLRAESASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPE