CYP2A6 Antilichaam - C-terminaal gebied: Biotine (ARP60126 P050-Biotine)

Cytochrome P450, family 2, subfamily A, polypeptide 6

CPA6, CYP2A, CYP2A3, P450PB, CYPIIA6, P450C2A

1548

P11509

NP_000753

Human, Horse

The immunogen is a synthetic peptide directed towards the C terminal region of human CYP2A6

CYP2A6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.

POR; CYB5A

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Horse: 83%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

56kDa

Wet Ice

494

CYP2A6

CYP2A6

Rabbit

Cytochrome P450 2A6

NM_000762

AFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKH