Cystatine E/CST6 Monoklonale Antilichaam

Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing in both a glycosylated (17 kDa) and an unglycosylated (14 kDa) form, with two characteristic intrachain disulfide bridges. Expression of cystatin M/E is found to be restricted to the epidermis, more specifically in the stratum granulosum, sweat glands, sebaceous glands, and the hair follicles. In addition to its function as a cysteine protease inhibitor, cystatin M/E also serves as a target for cross-linking by transglutaminases. Accordingly, cystatin M/E was suggested to be involved in barrier formation and maintenance. Furthermore, studies have revealed that cystatin M/E is frequently epigenetically inactivated during breast carcinogenesis, and thus be regarded as a candidate of tumour suppressor gene.

CST6

Q15828

Human

Recombinant Human Cystatin E / CST6 protein

CST 6; Cystatin 6; Cystatin E; Cystatin E/M; Cystatin M; Cystatin M/E; Cystatin6; Cystatin-6; CystatinE; Cystatin-E; CystatinM; Cystatin-M; Cysteine proteinase inhibitor; CYTM; CST6

6G11

Unconjugated

IHC-P

Cell Biology

Protein A

1 mg/mL

IHC-P 1:50-1:200

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/r3GAODbU

IgG1