
Cytarabine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells.1,2 It Cellular enzymes convert it to its nucleotide form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it.3,4 For the same reasons, it is also employed as an antiviral.5 It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML) .6,7
Unconjugated
White or off-white solid
-20°C
Beschrijving
Cytarabine Beschikbaar in 500 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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