CYTH1 Antilichaam

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants.

9267

Q15438

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH1 (NP_004753.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

Raji

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 46kDa

IgG

WB: 1:200 - 1:2000

CYTH1

Mouse brain

Mouse heart

Mouse spleen

Rat heart

Cytohesin 1

Homo sapiens

CYTH1, B2-1, Cytohesin 1, Cytohesin-1, Cytoadhesin 1, SEC7 homolog B2-1, SEC7, D17S811E, PSCD1

WB

Liquid