CYTH4 Antilichaam

This gene encodes a member of the PSCD family of proteins, which have an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family function as GEPs for ADP-ribosylation factors (ARFs), which are guanine nucleotide-binding proteins involved in vesicular trafficking pathways. This protein exhibits GEP activity in vitro with ARF1 and ARF5, but is inactive with ARF6. Alternatively spliced transcript variants have been found for this gene.

27128

Q9UIA0

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH4 (NP_037517.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

Mouse liver

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 46kDa

IgG

WB: 1:500 - 1:2000

CYTH4

Mouse brain

Rat brain

Cytohesin 4

Homo sapiens

PSCD4, CYT4, DJ63G5.1, CYTOHESIN-4, pleckstrin homology, Sec7 and coiled/coil domains 4, cytohesin-4, PSCD4

WB

Liquid