
Cytokeratine, pan (epitheliale markering)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
[KRT77]
374454
Human. Expected to show broad species reactivity.
Antibody with azide - store at 2 to 8 degree C.<br>Antibody without azide - store at -20 to -80 degree C.<br>Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor. It is a broad spectrum anti pan-cytokeratin antibody, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
[KRT77; KRT77; K1B; KRT1B; KRT1B; CK-1B; K77]
[Cytokeratin, pan]
[keratin, type II cytoskeletal 1b; Keratin, type II cytoskeletal 1b; keratin, type II cytoskeletal 1b; keratin 77; Cytokeratin-1B; CK-1B; Keratin-77; K77; Type-II keratin Kb39]
194018511
NP_778253.2
NM_175078.2
Q7Z794



