Cytokeratine 18 Antilichaam [SB38b] (HRP)

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8) . The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 18 is a type I intermediate filament protein that exists as a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 is expressed in all simple type epithelia and basal cells of many squamous and non-epidermal epithelia and is often co-expressed with cytokeratin 8. Tissues from the gastrointestinal tract, respiratory tract, and urogenital tract as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

3875

P05783

P05783

Human

Recombinant N-terminal cytokeratin 18

[SB38b]

HRP

Primary Antibodies

Signal Transduction

Batch dependent

Supplied in a stock solution of 50% glycerol/50% PBS, pH 7.4; No preservative added

None

Blue Ice

Store vial at 2-8˚ C

IgG2b

Cytokeratin 18

Cytokeratin 18 Antibody [SB38b] for use in immunocytochemistry, ELISA, and western blotting assays.

KRT18

Keratin, type I cytoskeletal 18

Homo sapiens

CK 18, keratin 18

Flow

Liquid