Cytokeratine 8 Antilichaam [SB37b] (HRP)

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1-8) . The two keratin types share only 30% sequence homology. Keratins demonstrate tissue- and differentiation-specific expression profiles. Cytokeratin 8 belongs to the type B (basic) subfamily of keratins and exists in combination with keratin 18. It is expressed in all simple type epithelia tissues (e.g., liver, pancreas, kidney, gut epithelial lining) but not in stratified squamous epithelia. Cytokeratin 8 is also present in the majority of adenocarcinomas and ductal carcinomas but is absent in most squamous cell carcinomas.

3856

P05787

P05787

Human

Recombinant C-terminal cytokeratin 8

[SB37b]

HRP

Primary Antibodies

Cancer

Batch dependent

Supplied in a stock solution of 50% glycerol/50% PBS, pH 7.4; No preservative added

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

Cytokeratin 8

Cytokeratin 8 Antibody [SB37b] for use in immunohistochemistry / immunocytochemistry, ELISA, and western blotting assays.

KRT8

Keratin 8

Homo sapiens

CK 8, keratin 8

Flow, IP

Liquid