Cytokeratine 8 (KRT8) Muismonoklonale Antilichaam [Kloon ID: LBI2E4]

Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Carrier-free (BSA/glycerol-free) CK8 mouse monoclonal antibody, clone LBI2E4

CARD2; CK-8; CK8; CYK8; K2C8; K8; KO

Homo sapiens keratin 8 (KRT8), transcript variant 2, mRNA.

3856

P05787

Unconjugated

WB 1:500~1000, IHC 1:50, IF 1:50~100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

KRT8

https://www.ncbi.nlm.nih.gov/gene/?term=3856

https://www.uniprot.org/uniprot/P05787