D-Cateslytin

D-Cateslytin is an antimicrobial peptide that exhibits potent inhibition activity against Candida albicans (MIC = 2.9 μM) . D-Cateslytin can rapidly enter C. albicans, shows no cytotoxicity to human gingival fibroblasts, and is stable in saliva. D-Cateslytin can be used for research on Candida albicans related diseases, such as oral candidosis[1].

3002053-77-9

12352209

Fungal

Anti-infection

Infection

O=C(N[C@H](CO)C(N[C@H](CCSC)C(N[C@H](CCCNC(N)=N)C(N[C@H](CC(C)C)C(N[C@H](CO)C(N[C@H](CC1=CC=CC=C1)C(N[C@H](CCCNC(N)=N)C(N[C@H](C)C(N[C@H](CCCNC(N)=N)C(NCC(N[C@H](CC2=CC=C(C=C2)O)C(NCC(N[C@H](CC3=CC=CC=C3)C(N[C@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](CCCNC(N)=N)N

C81H130N30O19S

1860.15

[1]Dartevelle P, et al. D-Cateslytin: a new antifungal agent for the treatment of oral Candida albicans associated infections. Sci Rep. 2018 Jun 18;8 (1) :9235.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11170/

Peptides

No Development Reported