D, L-Buthionine Sulfoxime
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
D, L-Buthionine sulfoximine is an irreversible inhibitor of γ-glutamylcysteine ligase (GCL) . GCL is the first enzyme of the cellular glutathione biosynthetic pathway. Dysregulation of glutathione homeostasis is involved in many diseases including cancer, diabetes, neurodegenerative disorders and HIV/AIDS.1 Most disease states involve decreased glutathione synthesis, however, in cancer, it is increased supporting cellular proliferation and protecting cancer cells. Pharmacological inhibition of GCL has been examined as a potential cancer treatment.2-4
Unconjugated
White solid
-20°C
Beschrijving
D, L-Buthionine Sulfoxime Beschikbaar in 100 mg. Bestel eenvoudig online met snelle levering.
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