[D-Lys6]-LH-RH (TFA)

[D-Lys6]-LH-RH TFA is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH TFA acts as a GnRH receptor agonist[1].

12352209

GnRH Receptor

GPCR/G Protein

Cancer; Endocrinology

99.16

O=C([C@H]1NC(CC1)=O)N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N3[C@@H](CCC3)C(NCC(N)=O)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)CC5=CNC6=CC=CC=C56)=O.OC(C(F)(F)F)=O.[x]

C59H84N18O13.xC2HF3O2

1253.41 (free base)

[1]Pinski J, et al. Inhibition of growth of experimental prostate cancer in rats by LH-RH analogs linked to cytotoxic radicals. Prostate. 1993;23 (2) :165-78.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P3668A/

Peptides

No Development Reported