D-α-methyl-DOPA
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
D-α-Methyl DOPA is an inhibitor of the binding of DQ8 peptide to MHC class II molecules. D-α-Methyl DOPA occupies a pocket along the DQ8 peptide binding groove. D-α-Methyl DOPA inhibits the binding of a DQ8 peptide to an MHC class II molecule for presentation to CD4+ T cells, thereby slowing the development or progression of type 1 diabete or celiac disease[1].
2799-15-7
12352005
H302-H312-H332
MHC
Immunology/Inflammation
Inflammation/Immunology; Metabolic Disease
OC1=CC(=CC=C1O)C[C@](N)(C)C(O)=O
C10H13NO4
211.21
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
[1]Peter A, et al. Methods of treating autoimmune disease. WO2017165508A1. WIPO (PCT) . 2017-03-22.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W387035/
Reference compound2
No Development Reported
MHC II
Beschrijving
D-α-Methyl DOPA is an inhibitor of the binding of DQ8 peptide to MHC class II molecules. D-α-Methyl DOPA occupies a pocket along the DQ8 peptide binding groove.
Specificaties
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