Dactolisib (BEZ235)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
915019-65-7
NVP-BEZ235
C07430-50mg
ATM/ATR
PI3K/Akt/mTOR
CC (C) (C#N) C1=CC=C (C=C1) N2C3=C4C=C (C=CC4=NC=C3N (C2=O) C) C5=CC6=CC=CC=C6N=C5
C30H23N5O
Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR (p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2.
2 years -80 in solvent
Beschrijving
Dactolisib (BEZ235) Beschikbaar in 50 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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