Daeatal

Daeatal (Dynorphin A ethylamide (1-9) ) is an ethylamine-modified dynorphin fragment that can be used in the study of analgesia, addiction, depression, etc. Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS) . Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR) . Dynorphin A can induce neuronal death, and can be used in the research of neurological disease[1].

103614-28-4

Dynorphin A ethylamide (1-9)

12352209

Opioid Receptor

GPCR/G Protein; Neuronal Signaling

Neuroscience-Neuromodulation

Neurological Disease

OC(C=C1)=CC=C1C[C@H](NC)C(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N(C)[C@@H](CCCNC(N)=N)C(N[C@H](CC(C)C)C(N[C@H](C(NCC)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O

C56H93N19O10

1192.46

[1]Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160 (2) :361-75.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P1625/

Peptides

No Development Reported