DAF Antilichaam

The decay-accelerating factor (DAF), also known as CD55, is an integral membrane glycoprotein that is involved in the regulation of the complement cascade (1) . DAF limits excessive complement activation by accelerating their decay following DAF binding, thereby disrupting the cascade and preventing damage to host cells (2) . Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) (3) .

1604

P08174

NP_001108224

Human

Unconjugated

Primary Antibodies

Immunology

DAF antibody is affinity chromatography purified via peptide column.

Cat. No. 1203 - A549 Cell Lysate

1 mg/mL

DAF antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

DAF antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

DAF antibody is human specific. At least two isoforms of DAF are known to exist; this antibody will only detect the longest isoform.

CD55

Cat. No. 10-101 - Human Lung Tissue Slide

Cat. No. 1201 – HeLa Cell Lysate

CD55 molecule, decay accelerating factor for complement (Cromer blood group)

Homo sapiens

Nicholson-Weller A, March JP, Rosen CE, et al. Surface membrane expression by human blood leukocytes and platelts of decay-accelerating factor, a regulatory protein of the complement system. Blood 1985; 65:1237-44.

Seya T and Atkinson JP. Functional properties of membrane cofactor protein of complement. Biochem. J. 1989; 64:581-8.

Storry JR, Reid ME, and Yazer MH. The Cromer blood group system: a review. Immunohematology 2010; 109-18.

Decay-accelerating factor, CD55 molecule decay accelerating factor for complement (Cromer blood group), CD55, CR, TC, CROM

ELISA, WB, IHC-P, IF

168693643

Liquid