DAND5 Mouse Monoclonal Antibody [Kloon ID: LBI2H3]

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) DAND5 mouse monoclonal antibody, clone LBI2H3

CER2; CERL2; CKTSF1B3; COCO; CRL2; DANTE; GREM3; SP1

Homo sapiens DAN domain BMP antagonist family member 5 (DAND5), mRNA.

199699

Q8N907

Unconjugated

WB 1:500~2000, IHC 1:150, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

DAND5

https://www.ncbi.nlm.nih.gov/gene/?term=199699

https://www.uniprot.org/uniprot/Q8N907