
DAyne
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
DAyne is a Dopamine (DA) -mimetic probe. DAyne covalently binds to proteins modified by dopamine oxidation products (e.g., dopaquinone, DQ) to form adducts. DAyne is promising for research of Parkinson’s disease (PD), particularly neurotoxicity, protein modification, and related pathways (e.g., endoplasmic reticulum stress, cytoskeletal instability) caused by dopamine dysregulation[1].
1866495-46-6
12171500
Biochemical Assay Reagents
Others
Neurological Disease
OC1=C(O)C=CC(CCNCC#C)=C1
C11H13NO2
191.23
[1]Hurben AK, et al. Proteome-Wide Profiling of Cellular Targets Modified by Dopamine Metabolites Using a Bio-Orthogonally Functionalized Catecholamine. ACS Chem Biol. 2021 Nov 19;16 (11) :2581-2594.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-D2871/
Dye Reagents
No Development Reported
Beschrijving
DAyne is a Dopamine (DA) -mimetic probe. DAyne covalently binds to proteins modified by dopamine oxidation products (e.g., dopaquinone, DQ) to form adducts. DAy
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