DAZAP2 Antilichaam

DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.

9802

Q15038

Q15038

Human

This DAZAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the C-terminal region of human DAZAP2.

Unconjugated

Primary Antibodies

Other

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

17 kDa

Rabbit Ig

DAZAP2

DAZ-associated protein 2

Homo sapiens

Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

Kim, J.E., et al. Mol. Cell. Biol. 28 (2) :803-813 (2008)

Shi, Y.W., et al. Chin. Med. J. 120 (19) :1659-1665 (2007)

DAZ-associated protein 2, Deleted in azoospermia-associated protein 2, DAZAP2, KIAA0058

WB, IHC-P

44887865

Liquid