DBCO-PEG2-Val-Cit-PAB-MMAE
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2845934-59-8
ADC Linker
Antibody-drug Conjugate/ADC Related
DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB moiety, and an MMAE payload. The DBCO group serves as a click chemistry handle that can react with azide groups, while the Val-Cit dipeptide is protease-cleavable, enabling the release of the MMAE payload into cells through an elimination mechanism.
C(CCC(NCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(=O)N2[C@]([C@@H]([C@H](C(N[C@@H]([C@@H](O)C3=CC=CC=C3)C)=O)C)OC)(CCC2)[H])OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)C)=O)C=C1)=O)CCCNC(N)=O)=O)[C@H](C)C)=O)=O)(=O)N4C=5C(C#CC=6C(C4)=CC=CC6)=CC=CC5
C84H120N12O17
1569.92
Ice Packs
-20°C
Beschrijving
DBCO-PEG2-Val-Cit-PAB-MMAE Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
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