DBT Mouse Monoclonal Antibody [Kloon ID: LBI1G2]

The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]

Carrier-free (BSA/glycerol-free) DBT mouse monoclonal antibody, clone LBI1G2

BCATE2; BCKAD-E2; BCKADE2; BCOADC-E2; E2; E2B

Homo sapiens dihydrolipoamide branched chain transacylase E2 (DBT), mRNA; nuclear gene for mitochondrial product.

1629

P11182

Unconjugated

Metabolic pathways, Valine, leucine and isoleucine degradation

Metabolic pathways, Valine, leucine and isoleucine degradation

WB 1:2000, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

DBT

https://www.ncbi.nlm.nih.gov/gene/?term=1629

https://www.uniprot.org/uniprot/P11182