DC-5163
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
DC-5163 is a potent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with an IC50 of 176.3 nM and a Kd of 3.192 μM. DC-5163 can inhibit glycolysis pathway partially. DC-5163 also selectively inhibits cancer cell proliferation and induces apoptosis[1].
897771-47-0
12352005
Apoptosis
Apoptosis
Cancer-programmed cell death
Cancer
99.30
DMSO : 300 mg/mL (ultrasonic)
S=C(N1CCN(CC2=CC=CC=C2)C1)NC3=CC=C(OC)C(Cl)=C3
C18H20ClN3OS
361.89
[1]Li T, et al. Discovery of novel glyceraldehyde-3-phosphate dehydrogenase inhibitor via docking-based virtual screening. Bioorg Chem. 2020 Mar;96:103620.
Room Temperature
-20°C, 3 years; 4°C, 2 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-43643/DC-5163-SDS-MedChemExpress.pdf
Reference compound1
No Development Reported
Beschrijving
DC-5163 is a potent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with an IC50 of 176.3 nM and a Kd of 3.192 μM. DC-5163 can inhibit glycolysis pat
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