DDC4002
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
DDC4002 is a selective EGFR inhibitor. DDC4002 has inhibitory activity against the L858R/T790M mutant EGFR subtype (IC50 = 39 nM) [1].
2375048-04-5
12352005
EGFR
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Others
O=C1C=2C=CC=CC2NC3=CC=C(F)C=C3N1CC=4C=CC=CC4
C20H15FN2O
318.35
[1]De Clercq DJH, et al. Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors. ACS Med Chem Lett. 2019 Oct 22;10 (11) :1549-1553.
Room temperature
Reference compound1
No Development Reported
Beschrijving
DDC4002 is a selective EGFR inhibitor. DDC4002 has inhibitory activity against the L858R/T790M mutant EGFR subtype (IC50 = 39 nM) [1].
Specificaties
Recent bekeken producten
Optical EtBr filter, 610 nm for SmartView Pro Imager System, 1100 & 2100 series (for UV)
UVCI-1100-EB
1 Unit
AGPAT4 Antibody
MBS7124622-01
0.05 mL
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315
125 mL
SCD polyclonal antibody
GTR18043932-01
50 μL
(KO Validated) SUMO1 Polyclonal Antibody
E-AB-92410-01
60 µL
Salicylate hydroxylase, Microorganism
HY-E70520-01
1 KU
Purified Diphtheria Toxoid protein (cGMP/USP, vaccine grade, ~1500-2500 Lf/ml; Low endotoxin)
DTOX16-N-500
500 µg
BioCoupler® Glass Set (16 oz) x12
BCS1612
12 Each
Recent gezochte producten
Total BDNF Quantikine ELISA Kit
DBNT00
96 Tests
Quantikine Immunoassay Control Set 885 for Total BDNF
QC218
1 Set
Total BDNF Quantikine SixPak (6 Plates)
SBNT00
6x 96 Tests
Rabbit Polyclonal BDNF Antibody
NB100-98682SS
0.025 mL
Polyclonal BDNF Antibody (CT)
APG02267G
0.1ml
Polyclonal BDNF Antibody
APG02253G
0.05mg
Polyclonal BDNF Antibody
APG02256G
0.1mg
Polyclonal BDNF Antibody
APG02257G
0.05ml