DDIT3 Antilichaam - N-terminalgebied: FITC (ARP31591_P050-FITC)

DNA-damage-inducible transcript 3

CHOP, CEBPZ, CHOP10, CHOP-10, GADD153, AltDDIT3, C/EBPzeta

1649

F8VS99

NP_001181985

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the N-terminal region of Human DDIT3

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

CCDC153; ATPAF2; ZC3H14; TRIB3; C11orf30; BATF3; VPS37C; AMOTL2; HSD17B14; SNAPC5; HDAC5; HDAC6; TNFSF12; ZBTB25; UBC; LMO2; HDAC1; FOSL2; EP300; CEBPG; C14orf80; GIPC1; BATF; ATF4; PPIB; MAFF; CREB3; FOSL1; NFIL3; MAFG; JUNB; JUN; FOS; EPAS1; DDIT3; DBP

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB, IHC

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 86%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 92%; Sheep: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21kDa

Wet Ice

192

DDIT3

DDIT3

Rabbit

DNA damage-inducible transcript 3 protein Ensembl ENSP00000447803 Ensembl ENSP00000448665

SLPFSFGTLSSWELEAWYEDLQEVLSSDENGGTYVSPPGNEEEESKIFTT