DDX17 Antilichaam - N-terminaal gebied: Biotine (ARP36388 P050-Biotin)

DEAD (Asp-Glu-Ala-Asp) box helicase 17

P72, RH70

10521

Q92841

NP_006377

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human DDX17

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The DEAD box protein is an ATPase activated by a variety of RNA species but not by dsDNA. This protein and that encoded by DDX5 gene are more closely related to each other than to any other member of the DEAD box family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene.

BYSL; GRB2; RBM15; CEP250; UBC; SUMO2; SUMO3; SPRTN; STAU1; CDC37; IVNS1ABP; SUMO1; LGR4; MDM2; NEDD8; RPA3; RPA2; RPA1; WWOX; EED; rev; P3H1; LSM1; PRPSAP1; PIN1; DDX5; APBB1; PARK2; FBXO6; TARDBP; WBP11; SF1; UBD; IGSF8; ICAM1; CD81; SF3B4; WHSC1; VCAM1

Biotin

Polyclonal Antibody

WB

Affinity Purified

DDX17 is strongly supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

80kDa

Chen, G., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (11), 4352-4357

Wet Ice

729

DDX17

DDX17

Rabbit

Probable ATP-dependent RNA helicase DDX17

NM_006386

PKKFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKK