DDX23 Antilichaam - C-terminal regio : HRP (ARP36376_T100-HRP)

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

Prp28, PRPF28, U5-100K, SNRNP100, U5-100KD

9416

Q9BUQ8

NP_004809

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human DDX23

DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.

SUMO2; STAU1; UBC; RPA3; RPA2; RPA1; ERG; SUZ12; WBP4; PRPF4B; PAXIP1; PHF5A; SF3A3; SART1; THOC5; PURA; RNU6ATAC; RNU4ATAC; TERF2IP; TERF1; SIRT7; HNRNPA1; SF3A2; SUMO1; Prpf8; TOP1; SNW1; TP63; TP73; MEPCE; USP39; PRPF4; OTUB1; RNPS1; CD2BP2

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

DDX23 is strongly supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

90kDa

Teigelkamp, S., et al., (1997) RNA 3 (11), 1313-1326

Wet Ice

820

DDX23

DDX23

Rabbit

Probable ATP-dependent RNA helicase DDX23

NM_004818

EDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA