DDX42 Antilichaam - N-terminalgebied: FITC (ARP36403 P050-FITC)

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

RHELP, RNAHP, SF3B8, DDX42P, SF3b125

11325

Q86XP3

NP_031398

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human DDX42

DDX42 is a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX42 is a ATP-dependent RNA helicase. DDX42 binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. It also mediates RNA duplex formation thereby displacing the single-strand RNA binding protein.This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.

FUS; UBC; SUMO1; EED; SHFM1; FBXO25; LMNA; PRPF19; U2SURP; SF3A1; SF3B4; SNRPC; ITGA4; DHX15; PIN4; KAL1; EPRS; APP; PHF20; NOSIP; RPL36; FOXJ3; TCERG1; SYNCRIP; RPS6KA4; SUMO3; ISG15; SIRT7; SF3A2; MEPCE; RUVBL2; RUVBL1; RECQL5; SF3B1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

103kDa

Will, C.L., et al., (2002) EMBO J. 21 (18), 4978-4988

Wet Ice

938

DDX42

DDX42

Rabbit

ATP-dependent RNA helicase DDX42

NM_007372

PLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYM