DDX48 Antilichaam - middelste regio : HRP (ARP36422 T100-HRP)

Eukaryotic translation initiation factor 4A3

Fal1, RCPS, DDX48, MUK34, NUK34, NMP265, eIF4AIII, eIF4A-III, eIF-4A-III

9775

P38919

NP_055555

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human DDX48

DDX48 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

CDCA7L; PDCD4; HUWE1; POLDIP3; HAUS1; SUMO2; SUMO3; STAU1; UBC; LIN28B; SUMO1; WWOX; EED; RNF2; BMI1; SUZ12; ANP32A; PKM; NPLOC4; IPO11; PDLIM5; PLIN3; SRP14; RAD23B; AARS; FBXO6; SRPK2; SRPK1; UPF1; SMG1; RBM8A; ITGA4; CWC22; EEF2K; VCAM1; FN1; TRA2B; HN

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

EIF4A3 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

45kDa

Lee, S., et al., (2002) Cancer Lett. 184 (2), 197-206

Wet Ice

411

EIF4A3

EIF4A3

Rabbit

Eukaryotic initiation factor 4A-III

NM_014740

QCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLV