DDX5 Antilichaam - C-terminal regio : HRP (ARP36365_T100-HRP)

DEAD (Asp-Glu-Ala-Asp) box helicase 5

P68, HLR1, G17P1, HUMP68

1655

P17844

NP_004387

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human DDX5

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX5 encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. DDX5 consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.

FUS; ESR1; DROSHA; MAPKAPK2; UBC; TP53; TUBGCP3; AURKB; SPRTN; AURKA; SUMO2; SUMO3; MDM2; CEP250; STAU1; RPA3; RPA2; RPA1; EED; EZH2; RNF2; SUZ12; rev; DDX17; PABPC4; PRPSAP1; PIN1; LRSAM1; FKBP10; ERO1L; DBNL; WDR4; PARK2; FBXO6; MAPK10; SP1; TARDBP; UBD

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

DDX5 is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

68kDa

Guil, S., et al., (2003) Mol. Cell. Biol. 23 (8), 2927-2941

Wet Ice

614

DDX5

DDX5

Rabbit

Probable ATP-dependent RNA helicase DDX5

NM_004396

SFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAY