DDX50 Antilichaam - N-terminaal gebied: Biotine (ARP36496_P050-Biotine)

DEAD (Asp-Glu-Ala-Asp) box polypeptide 50

GU2, GUB, mcdrh, RH-II/GuB

79009

Q9BQ39

NP_076950

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig

The immunogen is a synthetic peptide directed towards the N terminal region of human DDX50

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX50 is a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.

SUMO3; UBC; LIN28A; PRKRA; TARBP2; EED; RNF2; TARDBP; SRPK2; WHSC1; KRAS; ESR1; BARD1; CAND1; CUL3; HDGF; STAU1; SRRM2

Biotin

Polyclonal Antibody

WB

Affinity Purified

DDX50 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 86%; Guinea Pig: 77%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 86%; Rat: 92%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

82kDa

Olsen, J.V., (2006) Cell 127 (3), 635-648

Wet Ice

737

DDX50

DDX50

Rabbit

ATP-dependent RNA helicase DDX50

NM_024045

PGKLLWGDIMELEAPLEESESQKKERQKSDRRKSRHHYDSDEKSETRENG