DE 17F

IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant human IL-17F is a disulfide-linked homodimer of 30.1 kDa, consisting of two 133 amino acid residue chains.

Cytokine ML-1; IL-17F; ILN; Interleukin; Interleukin-17F; interleukin-24; Interleukin17F; mutant IL-17F

64806

Q96PD4

NP_443104.1

NM_052872.3

14q11.2

Human

Human

MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Measured by its ability to induce IL-6 production by NHDF cells.

133

Lyophilized

30.1 kDa

E. coli