Debrisoquin (hydrobromide)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Debrisoquine (Ro 5-3307/1) hydrobromide is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an IC50 of 22μM. Debrisoquine hydrobromide can be used for antiviral research[1].
1131-65-3
Debrisoquine (hydrobromide) ; Isocaramidine (hydrobromide) ; Ro 5-3307/1 (hydrobromide)
12352005
SARS-CoV; Ser/Thr Protease
Anti-infection; Metabolic Enzyme/Protease
COVID-19-anti-virus
Infection
N=C(N1CC2=C(CC1)C=CC=C2)N.Br
C10H14BrN3
256.14
[1]Amanda L. Peiffer, et.al.TMPRSS2 Inhibitor Discovery Facilitated through an In Silico and Biochemical Screening Platform.ACS Medicinal Chemistry Letters 2023 14 (6), 860-866.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-B1624C/
Reference compound1
No Development Reported
Beschrijving
Debrisoquine (Ro 5-3307/1) hydrobromide is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner, with an I
Specificaties
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