Decaninezuur-13C

Decanoic acid-13C is the 13C-labeled Decanoic acid. Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy[1][2][3].

84600-66-8

12352211

H302, H315, H319, H335

C-Met/HGFR; Glutaminase; iGluR; Isotope-Labeled Compounds; Tyrosinase

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Protein Tyrosine Kinase/RTK

Cancer; Metabolic Disease; Neurological Disease

99.30

DMSO : 100 mg/mL (ultrasonic)

CCCCCCCCC[13C](O)=O

C9 13CH20O2

173.26

H302, H315, H319, H335

[1]Boison D, et, al. New insights into the mechanisms of the ketogenic diet. Curr Opin Neurol. 2017 Apr;30 (2) :187-192.|[2]Warren EC, et al. Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling[J]. Proc Natl Acad Sci U S A. 2020 Sep 22;117 (38) :23617-23625.|[3]Yang MH, et al. Decanoic Acid Exerts Its Anti-Tumor Effects via Targeting c-Met Signaling Cascades in Hepatocellular Carcinoma Model[J]. Cancers (Basel) . 2023 Sep 22;15 (19) :4681.

Room Temperature

Store at room temperature 3 years

http://file.medchemexpress.com/batch_PDF/HY-W266188/Decanoic-acid-13C-SDS-MedChemExpress.pdf

Isotope-Labeled Compounds

No Development Reported