Defensin / Beta-defensin 3 / DEFB103 Proteïne (Zijn label)

Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. It is also expressed in salivary gland, bone marrow, colon, stomach, polyp and larynx. However, in small intestine, it cannot be detected. Defensin has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. Beta-defensin 3 kills multiresistant S.aureus and vancomycin-resistent E.faecium. It has no significant hemolytic activity.

BD-3 Protein; BD3 Protein; DEFB-3 Protein; DEFB103 Protein; DEFB103B Protein; DEFB3 Protein; DEFB3; Protein; HBD-3 Protein; HBD3 Protein; HBP-3 Protein; HBP3 Protein

P81534

Human

Human

His-Tag

See Datasheet send with the product

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> 95 % as determined by SDS-PAGE

Data not available

61

Lyophilized or frozen liquid

50mM Tris, 0.3% Triton X-100, 0.3% SKL, pH 8.5

See Datasheet

12 kDa

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

E.coli